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ShareMSA: real time collaboration on multiple sequence alignments

Abstract

A Multiple Sequence Alignment (MSA) is a widely used data structure in bioinformatics for applications ranging from evolutionary analyses to protein engineering. ShareMSA is a website that allows users to visualize, share, and collaborate on MSAs. ShareMSA makes MSAs more accessible by allowing collaborators one-click access to the MSA and annotations without the need to install software. In addition, when those with requisite permissions change the annotations or legend, all viewers of the MSA see the changes in real time. A Chimera plugin is available via the ShareMSA website, allowing Chimera users to publish MSAs from within this sequence-structure visualization software.

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