Skip to main content
Open Access Publications from the University of California


UCLA Previously Published Works bannerUCLA

Pathophysiology, classification, and MRI parallels in microvascular disease of the heart and brain.

  • Author(s): Thomas, Michael A
  • Hazany, Saman
  • Ellingson, Benjamin M
  • Hu, Peng
  • Nguyen, Kim-Lien
  • et al.

Published Web Location
No data is associated with this publication.

Diagnostic imaging technology in vascular disease has long focused on large vessels and the pathologic processes that impact them. With improved diagnostic techniques, investigators are now able to uncover many underlying mechanisms and prognostic factors for microvascular disease. In the heart and brain, these pathologic entities include coronary microvascular disease and cerebral small vessel disease, both of which have significant impact on patients, causing angina, myocardial infarction, heart failure, stroke, and dementia. In the current paper, we will discuss parallels in pathophysiology, classification, and diagnostic modalities, with a focus on the role of magnetic resonance imaging in microvascular disease of the heart and brain. Novel approaches for streamlined imaging of the cardiac and central nervous systems including the use of intravascular contrast agents such as ferumoxytol are presented, and unmet research gaps in diagnostics are summarized.

Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.

Item not freely available? Link broken?
Report a problem accessing this item