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PiVR: An affordable and versatile closed-loop platform to study unrestrained sensorimotor behavior

Published Web Location

https://doi.org/10.1371/journal.pbio.3000712
Abstract

Tools enabling closed-loop experiments are crucial to delineate causal relationships between the activity of genetically labeled neurons and specific behaviors. We developed the Raspberry Pi Virtual Reality (PiVR) system to conduct closed-loop optogenetic stimulation of neural functions in unrestrained animals. PiVR is an experimental platform that operates at high temporal resolution (70 Hz) with low latencies (<30 milliseconds), while being affordable (

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