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Open Access Publications from the University of California

Identification and characterization of OSTL (RNF217) encoding a RING-IBR-RING protein adjacent to a translocation breakpoint involving ETV6 in childhood ALL

  • Author(s): Muschen, Markus
  • Fontanari, LM
  • Japp, AS
  • Krause, A
  • Mooster, J
  • Chopra, M
  • Müschen, M
  • Bohlander, SK
  • et al.

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Genomic aberrations involving ETV6 on band 12p13 are amongst the most common chromosomal abnormalities in human leukemia. The translocation t(6;12)(q23;13) in a childhood B-cell acute lymphoblastic leukemia (ALL) cell line fuses ETV6 with the putative long

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