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Open Access Publications from the University of California

Virus-PEDOT nanowires for biosensing

  • Author(s): Arter, JA
  • Taggart, DK
  • McIntire, TM
  • Penner, RM
  • Weiss, GA
  • et al.

Published Web Location Commons Attribution 4.0 International Public License

The separate fields of conducting polymer-based electrochemical sensors and virus-based molecular recognition offer numerous advantages for biosensing. Grafting M13 bacteriophage into an array of poly (3,4-ethylenedioxythiophene) (PEDOT) nanowires generated hybrids of conducting polymers and viruses. The virus incorporation into the polymeric backbone of PEDOT occurs during electropolymerization via lithographically patterned nanowire electrodeposition. The resultant arrays of virus-PEDOT nanowires enable real-time, reagent-free electrochemical biosensing of analytes in physiologically relevant buffers. © 2010 American Chemical Society.

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