UC Santa Cruz
Visualizing the structure and mechanism of a small nucleolytic ribozyme
- Author(s): Scott, WG
- et al.
Published Web Locationhttps://doi.org/10.1016/S1046-2023(02)00237-2
Time-resolved crystallography has recently evolved into a powerful and invaluabletechnique for observing conformational and chemical intermediate states ator near atomic resolution in protein enzymes. The application of monochromatic time-resolved X-ray crystallographic freeze-trapping experiments to an RNA enzyme, the hammerhead ribozyme, is outlined here. © 2002 Elsevier Science (USA). All rights reserved.
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