Medical Student Research Forum Posters

Stereo-electroencephalography (SEEG) is a commonly used method for intracranial monitoring in patients with medically intractable epilepsy. Depth electrodes are inserted to localize seizure onset zones and map epileptic and neural networks in order to plan further therapeutic surgeries such as resection or neuromodulation.

Due to the placement of SEEG electrodes in deep brain structures, accuracy is important to ensure the intended areas are sampled and to minimize complications. Various methods exist for placement, and can be broadly classified into frameless and frame-based methods. The former includes roboticassisted insertion and frameless navigation guidance systems, and the latter most commonly includes Leksell and CRW frame-based insertion. Despite the widespread use of these techniques, a recent meta-analysis was unable to find superiority of one method over the others.

We aimed to compare the accuracy, precision, and safety of these methods. We hypothesized that frame-based insertion would be more accurate and precise as compared to frameless insertion, with equal safety profiles for the two techniques.