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Decoupling of the PI3K pathway via mutation necessitates combinatorial treatment in HER2+ breast cancer
Published Web Location
http://europepmc.org/articles/PMC4504492?pdf=renderNo data is associated with this publication.
Abstract
© 2015 Korkola et al.We report here on experimental and theoretical efforts to determine how best to combine drugs that inhibit HER2 and AKT in HER2+ breast cancers. We accomplished this by measuring cellular and molecular responses to lapatinib
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