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Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch

Published Web Location

http://europepmc.org/articles/PMC4954757?pdf=render
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Abstract

© Gallagher et al.The membrane-bound transcription factor ATF6α plays a cytoprotective role in the unfolded protein response (UPR), required for cells to survive ER stress. Activation of ATF6α promotes cell survival in cancer models. We used cell-based scr

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