Skip to main content
eScholarship
Open Access Publications from the University of California

Optimizing Neuro-Oncology Imaging: A Review of Deep Learning Approaches for Glioma Imaging.

  • Author(s): Shaver, Madeleine M
  • Kohanteb, Paul A
  • Chiou, Catherine
  • Bardis, Michelle D
  • Chantaduly, Chanon
  • Bota, Daniela
  • Filippi, Christopher G
  • Weinberg, Brent
  • Grinband, Jack
  • Chow, Daniel S
  • Chang, Peter D
  • et al.
Abstract

Radiographic assessment with magnetic resonance imaging (MRI) is widely used to characterize gliomas, which represent 80% of all primary malignant brain tumors. Unfortunately, glioma biology is marked by heterogeneous angiogenesis, cellular proliferation, cellular invasion, and apoptosis. This translates into varying degrees of enhancement, edema, and necrosis, making reliable imaging assessment challenging. Deep learning, a subset of machine learning artificial intelligence, has gained traction as a method, which has seen effective employment in solving image-based problems, including those in medical imaging. This review seeks to summarize current deep learning applications used in the field of glioma detection and outcome prediction and will focus on (1) pre- and post-operative tumor segmentation, (2) genetic characterization of tissue, and (3) prognostication. We demonstrate that deep learning methods of segmenting, characterizing, grading, and predicting survival in gliomas are promising opportunities that may enhance both research and clinical activities.

Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.

Main Content
Current View