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SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer

Published Web Location

http://europepmc.org/articles/PMC4122675?pdf=render
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Abstract

Deregulation of lysine methylation signalling has emerged as a common aetiological factor in cancer pathogenesis, with inhibitors of several histone lysine methyltransferases (KMTs) being developed as chemotherapeutics. The largely cytoplasmic KMT SMYD3 (S

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