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SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer

  • Author(s): Butte, Atul
  • Mazur, PK
  • Reynoird, N
  • Khatri, P
  • Jansen, PWTC
  • Wilkinson, AW
  • Liu, S
  • Barbash, O
  • Van, GS
  • Huddleston, M
  • Dhanak, D
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4122675?pdf=render
No data is associated with this publication.
Abstract

Deregulation of lysine methylation signalling has emerged as a common aetiological factor in cancer pathogenesis, with inhibitors of several histone lysine methyltransferases (KMTs) being developed as chemotherapeutics. The largely cytoplasmic KMT SMYD3 (S

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