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Neither T-helper type 2 nor Foxp3+ regulatory T cells are necessary for therapeutic benefit of atorvastatin in treatment of central nervous system autoimmunity

  • Author(s): Zamvil, Scott
  • Weber, MS
  • Prod'homme, T
  • Youssef, S
  • Dunn, SE
  • Steinman, L
  • Zamvil, SS
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3922392?pdf=render
No data is associated with this publication.
Abstract

Oral atorvastatin has prevented or reversed paralysis in the multiple sclerosis (MS) model experimental autoimmune encephalomyelitis (EAE), and reduced development of new MS lesions in clinical trials. Besides inhibiting development of encephalitogenic T c

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