Investigating the role of transport processes in intracellular organization and dynamics
Transport of intracellular material is a fundamental process observed within the cells of organisms across all realms of life. While the biology may be vastly different across species, the physical mechanisms underlying motion remain largely consistent. Tubular cells such as neuronal axons and fungal hyphae are excellent systems to study transport owing to their simple geometry, robust transport machinery, and experimental tractability. We combine mathematical and computational approaches to explore how transport processes contribute to intracellular organization and affect biological function. Imaging data from neuronal and fungal cells are leveraged to develop functional models and verify their predictions.