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Open Access Publications from the University of California

An Uncommon Complication of Hepatitis A Virus Infection: A Case Report of Acute Inflammatory Demyelinating Polyneuropathy

  • Author(s): Laursen, Daniel
  • Krug, Jeffrey
  • Wolford, Robert
  • et al.
Creative Commons 'BY' version 4.0 license

Introduction: Acute inflammatory demyelinating polyneuropathy (AIDP) is characterized by progressive, mild sensory symptoms and progressive areflexic weakness. It typically follows a gastrointestinal or respiratory infection but has rarely been described after acute viral hepatitis.

Case Report: This is the case of a 59-year-old male who presented to the emergency department after acutely developing progressive neurologic symptoms following a hospitalization for acute hepatitis A. Cerebrospinal fluid analysis revealed albuminocytologic dissociation, and cervical spine magnetic resonance imaging revealed nerve root enhancement.

Discussion: The patient was diagnosed with AIDP, which is the most common subtype of Guillain-Barré syndrome in the United States and Europe. There have been few previously reported cases of AIDP following acute hepatitis A infection.

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