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Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment

  • Author(s): Baraban, Scott
  • Dinday, MT
  • Hortopan, GA
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3891590?pdf=render
No data is associated with this publication.
Abstract

Dravet syndrome is a catastrophic pediatric epilepsy with severe intellectual disability, impaired social development and persistent drug-resistant seizures. One of its primary monogenic causes are mutations in Na v 1.1 (SCN1A), a voltage-gated sodium chan

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