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Kinesin-5: A Team Is Just the Sum of Its Parts
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https://doi.org/10.1016/j.devcel.2015.09.010Abstract
How the cell builds a spindle remains an open question. In this issue of Developmental Cell, Shimamoto, Forth, and Kapoor (2015) show that kinesin-5 motor ensembles can exert sliding forces that scale with microtubule overlap length. This behavior could allow microtubule architecture-dependent modulation of force and contribute to spindle self-organization.
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