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Intracranial meningioma with carcinoma tumor-to-tumor metastasis: two case reports.

  • Author(s): Pham, Jason T
  • Kim, Ronald C
  • Nguyen, Anna
  • Bota, Daniela
  • Kong, Xiao-Tang
  • Vadera, Sumeet
  • Hsu, Frank
  • Carrillo, Jose A
  • et al.
Abstract

Meningiomas have been implicated as the most common primary intracranial tumor to contain tumor-to-tumor metastasis. In the following two case reports, we describe cases of adenocarcinoma and breast carcinoma that metastasized into an intracranial meningioma. The first patient was a 64-year-old man presenting to the emergency department with seizures and loss of consciousness. After a left frontal mass resection, pathology reported a heterogeneous mass consisting of a meningioma and a metastatic adenocarcinoma component. The second patient was a 63-year-old woman presenting with significant vision problems and unstable gait. After a right frontal mass resection, pathology reported a heterogeneous mass consisting of a meningioma and a metastatic breast carcinoma component. Possible explanations for the development of the tumor-to-tumor metastasis are described.

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