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Open Access Publications from the University of California

Tau reduction prevents Aβ-induced axonal transport deficits by blocking activation of GSK3β

  • Author(s): Mucke, Lennart
  • Vossel, KA
  • Xu, JC
  • Fomenko, V
  • Miyamoto, T
  • Suberbielle, E
  • Knox, JA
  • Ho, K
  • Kim, DH
  • Yu, GQ
  • et al.

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© 2015 Vossel et al.Axonal transport deficits in Alzheimer's disease (AD) are attributed to amyloid β (Aβ) peptides and pathological forms of the microtubuleassociated protein tau. Genetic ablation of tau prevents neuronal overexcitation and axonal transpo

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