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Fusion of a short peptide that binds immunoglobulin G to a recombinant protein substantially increases its plasma half-life in mice
Published Web Location
http://europepmc.org/articles/PMC4109916?pdf=renderNo data is associated with this publication.
Abstract
We explore a strategy to substantially increase the half-life of recombinant proteins by genetic fusion to FcIII, a 13-mer IgG-Fc domain binding peptide (IgGBP) originally identified by DeLano and co-workers at Genentech [DeLano WL, et al. (2000) Science 2
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