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A widening longevity gap between people with schizophrenia and general population: A literature review and call for action.

  • Author(s): Lee, Ellen E
  • Liu, Jinyuan
  • Tu, Xin
  • Palmer, Barton W
  • Eyler, Lisa T
  • Jeste, Dilip V
  • et al.

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Individuals with schizophrenia have higher mortality rates than the population at large. General mortality rates have declined in developed countries since the early 1970s, extending average lifespan by nearly a decade. This review of eight longitudinal studies of mortality in schizophrenia found that the mean standardized mortality ratio (SMR, a measure of mortality rate in schizophrenia compared to the general population) increased 37%, from 2.2 in the pre-1970s studies to 3.0 in the post-1970s reports. Major changes in societal stigma, healthcare, and economic policy are urgently warranted to ensure that this vulnerable segment of the population participates in the longevity revolution.

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