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Novel Method Suggests Global Superiority of Short-Duration Antibiotics for Intra-abdominal Infections.
- Celestin, Arthur R;
- Odom, Stephen R;
- Angelidou, Konstantia;
- Evans, Scott R;
- Coimbra, Raul;
- Guidry, Christopher A;
- Cuschieri, Joseph;
- Banton, Kaysie L;
- O'Neill, Patrick J;
- Askari, Reza;
- Namias, Nicholas;
- Duane, Therèse M;
- Claridge, Jeffrey A;
- Dellinger, E Patchen;
- Sawyer, Robert A;
- Cook, Charles H
- et al.
Published Web Location
https://doi.org/10.1093/cid/cix569Abstract
Desirability of outcome ranking and response adjusted for duration of antibiotic risk (DOOR/RADAR) are novel and innovative methods of evaluating data in antibiotic trials. We analyzed data from a noninferiority trial of short-course antimicrobial therapy for intra-abdominal infection (STOP-IT), and results suggest global superiority of short-duration therapy for intra-abdominal infections.
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