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AUY922 effectively overcomes MET- And AXL-mediated resistance to EGFR-TKI in lung cancer cells

  • Author(s): Bivona, Trever
  • Choi, YJ
  • Kim, SY
  • So, KS
  • Baek, IJ
  • Kim, WS
  • Choi, SH
  • Lee, JC
  • Bivona, TG
  • Rho, JK
  • Choi, CM
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4363657?pdf=render
No data is associated with this publication.
Abstract

© 2015, public library of science. All rights reserved.The activation of bypass signals, such as MET and AXL, has been identified as a possible mechanism of EGFR-TKI resistance. Because various oncoproteins depend on HSP90 for maturation and stability, we

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