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Intrinsic Activity of Odorant Receptors Guides Sensory Map Formation
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https://doi.org/10.1016/j.cell.2013.08.037Abstract
Olfactory sensory neurons innervate the olfactory bulb in stereotyped patterns according to the odorant receptors they express. A study by Nakashima et al. in this issue demonstrates that the odorant receptor's level of intrinsic activity-in the absence of activating odorant-influences the guidance of olfactory axons to their targets.
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