Skip to main content
Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3+ regulatory T cells
- Pierson, Wim;
- Cauwe, Bénédicte;
- Policheni, Antonia;
- Schlenner, Susan M;
- Franckaert, Dean;
- Berges, Julien;
- Humblet-Baron, Stephanie;
- Schönefeldt, Susann;
- Herold, Marco J;
- Hildeman, David;
- Strasser, Andreas;
- Bouillet, Philippe;
- Lu, Li-Fan;
- Matthys, Patrick;
- Freitas, Antonio A;
- Luther, Rita J;
- Weaver, Casey T;
- Dooley, James;
- Gray, Daniel HD;
- Liston, Adrian
Published Web Location
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128388/No data is associated with this publication.
Abstract
The signals controlling Treg cell homeostasis and survival are still being determined. Liston and colleagues demonstrate that peripheral Treg cells depend critically on IL-2 and the survival factor Mcl-1 but not on Bcl-2.
Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.