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A global DNA methylation and gene expression analysis of early human B-cell development reveals a demethylation signature and transcription factor network

  • Author(s): Wiemels, Joseph;
  • Wiencke, John;
  • Lee, ST;
  • Xiao, Y;
  • Muench, MO;
  • Xiao, J;
  • Fomin, ME;
  • Wiencke, JK;
  • Zheng, S;
  • Dou, X;
  • De, A;
  • Chokkalingam, A
  • et al.

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The epigenetic changes during B-cell development relevant to both normal function and hematologic malignancy are incompletely understood. We examined DNA methylation and RNA expression status during early B-cell development by sorting multiple replicates o

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