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Open Access Publications from the University of California

L-Carnitine preserves endothelial function in a lamb model of increased pulmonary blood flow

  • Author(s): Fineman, Jeffrey
  • Oishi, Peter
  • Sharma, S
  • Aramburo, A
  • Rafikov, R
  • Sun, X
  • Kumar, S
  • Datar, SA
  • Raff, G
  • Xoinis, K
  • Kalkan, G
  • et al.

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Background: In our model of a congenital heart defect (CHD) with increased pulmonary blood flow (PBF; shunt), we have recently shown a disruption in carnitine homeostasis, associated with mitochondrial dysfunction and decreased endothelial nitric oxide syn

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