UC Irvine

This meta-analysis set out to integrate and reconcile the disparate research on inflammatory biomarkers and perinatal depressive symptoms, in order to better understand the role of inflammation and depressive symptoms surrounding pregnancy. Overall, a small positive effect with a trending p-value emerged. Small statistically significant effects emerged between several biomarkers indicative of inflammation and depressive symptoms, depending on which markers were included and when during pregnancy or post partum those biomarkers were collected.