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Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis.

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http://europepmc.org/articles/PMC4232470?pdf=render
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Abstract

G protein-coupled receptors (GPCRs) are well known to signal via cyclic AMP (cAMP) production at the plasma membrane, but it is now clear that various GPCRs also signal after internalization. Apart from its temporal impact through prolonging the cellular r

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