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A mitochondrion targeting fluorescent probe for imaging of intracellular superoxide radicals
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https://doi.org/10.1039/c5cc01075fAbstract
An amine-reactive fluorogenic molecule specifically turned on by superoxide radicals (O2˙(-)) was synthesized and coupled to a mitochondrial (MT) targeting peptide. The obtained probe showed superior uptake and MT targeting capabilities; and successfully detected the change in O2˙(-) levels in cells treated with chemical stimuli or single-walled carbon nanotubes.
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