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Structural basis of mRNA-cap recognition by Dcp1–Dcp2
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https://doi.org/10.1038/nsmb.3301Abstract
The structure of the S. pombe Dcp2–Dcp1 decapping enzyme complex with human activator PNRC2 and tight-binding cap analog reveals a new conformation and, along with kinetics analyses, provides insight into substrate recognition and mechanisms of activators.
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