Skip to main content
eScholarship
Open Access Publications from the University of California

Distinguishing patients with stage i lung cancer versus control individuals using serum mass profiling

  • Author(s): Hanas, JS
  • Peyton, MD
  • Lerner, MR
  • Lightfoot, SA
  • Deb, SJ
  • Hanas, RJ
  • Vu, NT
  • Kupiec, TC
  • Stowell, DE
  • Brackett, DJ
  • Dubinett, SM
  • Hocker, JR
  • et al.

Published Web Location

http://informahealthcare.com/doi/abs/10.3109/07357907.2014.883528
No data is associated with this publication.
Abstract

Serum mass profiling can discern physiological changes associated with specific disease states and their progression. Sera (86 total) from control individuals and patients with stage I nonsmall cell lung cancer or benign small pulmonary nodules were discriminated retrospectively by serum changes discerned by mass profiling. Control individuals were distinguished from patients with Stage I lung cancer or benign nodules with test sensitivities of 89% and 83%. Lung cancer patients versus those with benign nodules were distinguished with 80% sensitivity. This study exhibits progress toward a minimally-invasive aid in early detection of lung cancer and monitoring small pulmonary nodules for malignancy. Copyright © 2014 Informa Healthcare USA, Inc.

Many UC-authored scholarly publications are freely available on this site because of the UC Academic Senate's Open Access Policy. Let us know how this access is important for you.

Item not freely available? Link broken?
Report a problem accessing this item