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Simulated evolution of protein-protein interaction networks with realistic topology
Published Web Location
http://europepmc.org/articles/PMC3387198?pdf=renderNo data is associated with this publication.
Abstract
We model the evolution of eukaryotic protein-protein interaction (PPI) networks. In our model, PPI networks evolve by two known biological mechanisms: (1) Gene duplication, which is followed by rapid diversification of duplicate interactions. (2) Neofuncti
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