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Simulated evolution of protein-protein interaction networks with realistic topology

  • Author(s): Dill, Ken
  • Peterson, GJ
  • Pressé, S
  • Peterson, KS
  • Dill, KA
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3387198?pdf=render
No data is associated with this publication.
Abstract

We model the evolution of eukaryotic protein-protein interaction (PPI) networks. In our model, PPI networks evolve by two known biological mechanisms: (1) Gene duplication, which is followed by rapid diversification of duplicate interactions. (2) Neofuncti

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