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A wearable chemical-electrophysiological hybrid biosensing system for real-time health and fitness monitoring.

  • Author(s): Imani, Somayeh
  • Bandodkar, Amay J
  • Mohan, AM Vinu
  • Kumar, Rajan
  • Yu, Shengfei
  • Wang, Joseph
  • Mercier, Patrick P
  • et al.

Published Web Location

http://www.nature.com/ncomms/2016/160523/ncomms11650/pdf/ncomms11650.pdf
No data is associated with this publication.
Abstract

Flexible, wearable sensing devices can yield important information about the underlying physiology of a human subject for applications in real-time health and fitness monitoring. Despite significant progress in the fabrication of flexible biosensors that naturally comply with the epidermis, most designs measure only a small number of physical or electrophysiological parameters, and neglect the rich chemical information available from biomarkers. Here, we introduce a skin-worn wearable hybrid sensing system that offers simultaneous real-time monitoring of a biochemical (lactate) and an electrophysiological signal (electrocardiogram), for more comprehensive fitness monitoring than from physical or electrophysiological sensors alone. The two sensing modalities, comprising a three-electrode amperometric lactate biosensor and a bipolar electrocardiogram sensor, are co-fabricated on a flexible substrate and mounted on the skin. Human experiments reveal that physiochemistry and electrophysiology can be measured simultaneously with negligible cross-talk, enabling a new class of hybrid sensing devices.

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