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Cost-effectiveness analysis of behavioral interventions to improve vaccination compliance in homeless adults.

  • Author(s): Greengold, Barbara
  • Nyamathi, Adeline
  • Kominski, Gerald
  • Wiley, Dorothy
  • Lewis, Mary Ann
  • Hodge, Felicia
  • Singer, Mendel
  • Spiegel, Brennan
  • et al.
Abstract

To estimate the cost-effectiveness of three behavioral interventions provided to enhance hepatitis A virus (HAV) and hepatitis B virus (HBV) joint vaccination (HAV/HBV) compliance among homeless persons living in Los Angeles County.A cost-effectiveness analysis (CEA) based on data from a randomized trial where the costs and compliance data from the trial are incorporated into two Markov models, simulating the natural history of acute and chronic hepatitis infection, following HAV/HBV vaccination.Reductions in HBV-related disease is cost-effective to society and is associated with substantial improvements in quality of life.

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