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Open Access Publications from the University of California

Cost-effectiveness analysis of behavioral interventions to improve vaccination compliance in homeless adults

  • Author(s): Greengold, B
  • Nyamathi, A
  • Kominski, G
  • Wiley, D
  • Lewis, MA
  • Hodge, F
  • Singer, M
  • Spiegel, B
  • et al.

Aims: To estimate the cost-effectiveness of three behavioral interventions provided to enhance hepatitis A virus (HAV) and hepatitis B virus (HBV) joint vaccination (HAV/HBV) compliance among homeless persons living in Los Angeles County. Scope: A cost-effectiveness analysis (CEA) based on data from a randomized trial where the costs and compliance data from the trial are incorporated into two Markov models, simulating the natural history of acute and chronic hepatitis infection, following HAV/HBV vaccination. Conclusions: Reductions in HBV-related disease is cost-effective to society and is associated with substantial improvements in quality of life. © 2008 Elsevier Ltd. All rights reserved.

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