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Targeting class A and C serine β-lactamases with a broad-spectrum boronic acid derivative
Published Web Location
http://europepmc.org/articles/PMC4079326?pdf=renderNo data is associated with this publication.
Abstract
Production of β-lactamases (BLs) is the most widespread resistance mechanism adopted by bacteria to fight β-lactam antibiotics. The substrate spectrum of BLs has become increasingly broad, posing a serious health problem. Thus, there is an urgent need for
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