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A first line of defense against ER stress
Published Web Location
http://europepmc.org/articles/PMC3413362?pdf=renderNo data is associated with this publication.
Abstract
BiP is the predominant DnaK/Hsp70-type chaperone protein in the ER. It is required for folding and assembling newly synthesized ER client proteins, yet having too much BiP inhibits folding. In this issue, Chambers et al. (2012. J. Cell Biol. doi:10.1083/jc
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