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A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33
- Petersen, Gloria M;
- Amundadottir, Laufey;
- Fuchs, Charles S;
- Kraft, Peter;
- Stolzenberg-Solomon, Rachael Z;
- Jacobs, Kevin B;
- Arslan, Alan A;
- Bueno-de-Mesquita, H Bas;
- Gallinger, Steven;
- Gross, Myron;
- Helzlsouer, Kathy;
- Holly, Elizabeth A;
- Jacobs, Eric J;
- Klein, Alison P;
- LaCroix, Andrea;
- Li, Donghui;
- Mandelson, Margaret T;
- Olson, Sara H;
- Risch, Harvey A;
- Zheng, Wei;
- Albanes, Demetrius;
- Bamlet, William R;
- Berg, Christine D;
- Boutron-Ruault, Marie-Christine;
- Buring, Julie E;
- Bracci, Paige M;
- Canzian, Federico;
- Clipp, Sandra;
- Cotterchio, Michelle;
- de Andrade, Mariza;
- Duell, Eric J;
- Gaziano, J Michael;
- Giovannucci, Edward L;
- Goggins, Michael;
- Hallmans, Göran;
- Hankinson, Susan E;
- Hassan, Manal;
- Howard, Barbara;
- Hunter, David J;
- Hutchinson, Amy;
- Jenab, Mazda;
- Kaaks, Rudolf;
- Kooperberg, Charles;
- Krogh, Vittorio;
- Kurtz, Robert C;
- Lynch, Shannon M;
- McWilliams, Robert R;
- Mendelsohn, Julie B;
- Michaud, Dominique S;
- Parikh, Hemang;
- Patel, Alpa V;
- Peeters, Petra HM;
- Rajkovic, Aleksandar;
- Riboli, Elio;
- Rodriguez, Laudina;
- Seminara, Daniela;
- Shu, Xiao-Ou;
- Thomas, Gilles;
- Tjønneland, Anne;
- Tobias, Geoffrey S;
- Trichopoulos, Dimitrios;
- Van Den Eeden, Stephen K;
- Virtamo, Jarmo;
- Wactawski-Wende, Jean;
- Wang, Zhaoming;
- Wolpin, Brian M;
- Yu, Herbert;
- Yu, Kai;
- Zeleniuch-Jacquotte, Anne;
- Fraumeni, Joseph F;
- Hoover, Robert N;
- Hartge, Patricia;
- Chanock, Stephen J
Abstract
Stephen Chanock and colleagues identify three new susceptibility loci for pancreatic cancer on chromosomes 13q22.1, 1q32.1 and 5p15.33. The association signal at 13q22.1 maps to a large nongenic region, whereas the signals at 1q32.1 and 5p15.33 map near the NR5A2 gene and CPTM1L-TERT region, respectively.
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