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ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing
- Chen, Xingqi;
- Shen, Ying;
- Draper, Will;
- Buenrostro, Jason D;
- Litzenburger, Ulrike;
- Cho, Seung Woo;
- Satpathy, Ansuman T;
- Carter, Ava C;
- Ghosh, Rajarshi P;
- East-Seletsky, Alexandra;
- Doudna, Jennifer A;
- Greenleaf, William J;
- Liphardt, Jan T;
- Chang, Howard Y
Published Web Location
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509561/No data is associated with this publication.
Abstract
The covalent insertion of fluorophore-labeled DNA adaptors by Tn5 transposase into open chromatin allows its imaging and subsequent analysis by sequencing from exactly the same samples.
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