Predictors of pathologic outcome of focal FDG uptake in the parotid gland identified on whole-body FDG PET imaging.
- Author(s): Mabray, Marc C
- Behr, Spencer C
- Naeger, David M
- Flavell, Robert R
- Glastonbury, Christine M
- et al.
Published Web Locationhttps://doi.org/10.1016/j.clinimag.2015.07.005
The purpose was to test whether patient's primary malignancy type and presence of F-18-fluorodeoxyglucose (FDG)-avid cervical lymph node(s) are predictors of pathologic outcome of incidental focal FDG-avid parotid lesions.A retrospective cohort study of pathologically proven incidental cases was performed.Focal parotid FDG uptake in the setting of head and neck cancer/melanoma [odds ratio (OR)=24.6, P<.01], lymphoma (OR=7.2, P=.02), or FDG-avid cervical lymph node(s) (OR=3.6, P=.07) has a higher odds of representing metastases. No malignant primary parotid tumors were incidentally discovered.In patients with head and neck cancer/melanoma, lymphoma, or FDG-avid cervical lymph node(s), there were higher odds that focal parotid FDG uptake was a metastasis.