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Ocriplasmin for vitreoretinal diseases.

  • Author(s): Tsui, Irena;
  • Pan, Carolyn K;
  • Rahimy, Ehsan;
  • Schwartz, Steven D
  • et al.
Abstract

Fibronectin and laminin are clinically relevant plasmin receptors in the eye. Located at the vitreoretinal interface, they are cleaved by ocriplasmin (Microplasmin, ThromboGenics, Iselin, NJ), a novel ophthalmic medication. A series of clinical trials to study ocriplasmin for the treatment of vitreoretinal diseases such as vitreomacular traction, macular hole, and exudative age-related macular degeneration are underway. The results are promising and may impact patient care.

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