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Hyaluronan-CD44 interaction promotes c-Jun signaling and miRNA21 expression leading to Bcl-2 expression and chemoresistance in breast cancer cells

  • Author(s): Bourguignon, Lilly
  • Chen, L
  • Bourguignon, LYW
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3975292?pdf=render
No data is associated with this publication.
Abstract

MicroRNA-21 (miR-21) is associated with the development of solid tumors progression including breast cancer. In this study we investigated matrix hyaluronan (HA)-CD44 (a primary HA receptor) interaction with c-Jun N-Terminal Kinase (JNK)/c-Jun signaling in

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