Hyaluronan-CD44 interaction promotes c-Jun signaling and miRNA21 expression leading to Bcl-2 expression and chemoresistance in breast cancer cells
- Author(s): Bourguignon, Lilly
- Chen, L
- Bourguignon, LYW
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3975292?pdf=render
MicroRNA-21 (miR-21) is associated with the development of solid tumors progression including breast cancer. In this study we investigated matrix hyaluronan (HA)-CD44 (a primary HA receptor) interaction with c-Jun N-Terminal Kinase (JNK)/c-Jun signaling in