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Open Access Publications from the University of California

The changing face of low-risk prostate cancer: trends in clinical presentation and primary management.

  • Author(s): Cooperberg, Matthew R
  • Lubeck, Deborah P
  • Meng, Maxwell V
  • Mehta, Shilpa S
  • Carroll, Peter R
  • et al.

Early intervention for prostate cancer is associated with excellent long-term survival, but many affected men, especially those with low-risk disease characteristics, might not experience adverse impact to survival or quality of life were treatment deferred. We sought to characterize temporal trends in clinical presentation and primary disease management among patients with low-risk prostate cancer.Data were abstracted from the Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE), a disease registry of 8,685 men with various stages of prostate cancer. Included were 2,078 men who were diagnosed between 1989 and 2001 and had a serum prostate specific antigen

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