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Open Access Publications from the University of California

Viruses and the placenta: the essential virus first view.

  • Author(s): Villarreal, Luis P
  • et al.

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A virus first perspective is presented as an alternative hypothesis to explain the role of various endogenized retroviruses in the origin of the mammalian placenta. It is argued that virus-host persistence is a key determinant of host survival and the various ERVs involved have directly affected virus-host persistence.

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