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Auditory temporal processes in normal-hearing individuals and in patients with auditory neuropathy

  • Author(s): Michalewski, HJ
  • Starr, A
  • Nguyen, TT
  • Kong, YY
  • Zeng, FG
  • et al.
Abstract

Objective: To study objectively auditory temporal processing in a group of normal hearing subjects and in a group of hearing-impaired individuals with auditory neuropathy (AN) using electrophysiological and psychoacoustic methods. Methods: Scalp recorded evoked potentials were measured to brief silent intervals (gaps) varying between 2 and 50 ms embedded in continuous noise. Latencies and amplitudes of N100 and P200 were measured and analyzed in two conditions: (1) active, when using a button in response to gaps; (2) passive, listening, but not responding. Results: In normal subjects evoked potentials (N100/P200 components) were recorded in response to gaps as short as 5 ms in both active and passive conditions. Gap evoked potentials in AN subjects appeared only with prolonged gap durations (10-50 ms). There was a close association between gap detection thresholds measured psychoacoustically and electrophysiologically in both normals and in AN subjects. Conclusions: Auditory cortical potentials can provide objective measures of auditory temporal processes. Significance: The combination of electrophysiological and psychoacoustic methods converged to provide useful objective measures for studying auditory cortical temporal processing in normals and hearing-impaired individuals. The procedure used may also provide objective measures of temporal processing for evaluating special populations such as children who may not be able to provide subjective responses. © 2004 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

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