Herpes simplex virus-2 associated with a large fungating penile mass.
- Author(s): Bowman, Max S;
- Lang, Ursula E;
- Leslie, Kieron S;
- Amend, Gregory;
- Breyer, Benjamin N
- et al.
Published Web Locationhttps://doi.org/10.1016/j.eucr.2021.101594
A 48-year-old male with HIV/AIDS presented with an enlarging nodular lesion on the base of his penis. Histology revealed changes consistent with chronic viral infection and culture grew herpes simplex virus 2 (HSV-2). The lesion was refractory to valacyclovir and intralesional (IL) cidofovir therapy. Urology excised the mass and the defect was repaired primarily with good cosmetic result. Post-operative pathology confirmed HSV-2 despite the unusual appearance of the lesion consisting of nodular mass without gross ulceration.