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Herpes simplex virus-2 associated with a large fungating penile mass.

  • Author(s): Bowman, Max S;
  • Lang, Ursula E;
  • Leslie, Kieron S;
  • Amend, Gregory;
  • Breyer, Benjamin N
  • et al.
Abstract

A 48-year-old male with HIV/AIDS presented with an enlarging nodular lesion on the base of his penis. Histology revealed changes consistent with chronic viral infection and culture grew herpes simplex virus 2 (HSV-2). The lesion was refractory to valacyclovir and intralesional (IL) cidofovir therapy. Urology excised the mass and the defect was repaired primarily with good cosmetic result. Post-operative pathology confirmed HSV-2 despite the unusual appearance of the lesion consisting of nodular mass without gross ulceration.

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