Skip to main content
Download PDF
- Main
Ligand Synthesis for Hepatitis C Virus Internal Ribosome Entry Site
- Author(s): Wang, Zihao;
- Advisor(s): Hermann, Thomas;
- et al.
Abstract
Benzothiadiazines were synthesized and tested for their binding affinity with hepatitis C virus internal ribosome entry site subdomain IIa using FRET assay. The acetylated compound was designed to improve the solubility and explore the tautomerization involved in targeting the IIa subdomain. An optimized Cu2O catalyzed Ullmann reaction was developed for future use.
Main Content
For improved accessibility of PDF content, download the file to your device.
Enter the password to open this PDF file:
File name:
-
File size:
-
Title:
-
Author:
-
Subject:
-
Keywords:
-
Creation Date:
-
Modification Date:
-
Creator:
-
PDF Producer:
-
PDF Version:
-
Page Count:
-
Page Size:
-
Fast Web View:
-
Preparing document for printing…
0%