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A toxic epidermal necrolysis-like presentation of linear IgA bullous dermatosis treated with dapsone

  • Author(s): Nguyen, Julie K;
  • Koshelev, Misha V;
  • Gill, Bartley J;
  • Boulavsky, Jessica;
  • Diwan, Abdul Hafeez;
  • Dao Jr, Harry
  • et al.
Abstract

Linear IgA bullous dermatosis is a rare autoimmune vesiculobullous disease characterized by linear deposition of IgA along the basement membrane zone. It is classically idiopathic, but may also arise secondary to drug exposure. A heterogeneous spectrum of clinical features has been described, including a rare, morbid variant mimicking toxic epidermal necrolysis. Herein, we present a case of vancomycin-induced linear IgA bullous dermatosis that manifested clinically as toxic epidermal necrolysis and resolved with dapsone therapy.

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