Dermatology Online Journal

Infantile myofibromatosis is a rare disorder offibroblastic/myofibroblastic proliferation andrepresents the most frequent type of mesenchymaltumor in the neonatal period and primary infancy.Three clinical types have been described: solitary,multicentric, and generalized (with visceralinvolvement). A correct characterization of thehistopathology is essential to diagnose theseneoplasias in early infancy. We present a case ofmulticentric infantile myofibromatosis with regressionover time.