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Polarity, cell division, and out-of-equilibrium dynamics control the growth of epithelial structures

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http://europepmc.org/articles/PMC3812962?pdf=render
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Abstract

The growth of a well-formed epithelial structure is governed by mechanical constraints, cellular apicobasal polarity, and spatially controlled cell division. Here we compared the predictions of a mathematical model of epithelial growth with the morphologic

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