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Open Access Publications from the University of California

The Type III Secretion System Cleans up Its Act(in).

  • Author(s): Auerbuch, Victoria
  • et al.

Inflammasome-associated innate immune receptors sense host-cell targeting by the type III secretion system (T3SS) of pathogenic Yersinia. In this issue of Cell Host & Microbe, Chung et al. (2016) show that the Yersinia T3SS effector protein YopM counteracts this recognition pathway by restricting the pyrin inflammasome, thus increasing bacterial fitness.

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